Fast Simulation of Bayesian Optimal Interval Designs for Phase I Trials

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Documentation for package ‘simFastBOIN’ version 2.1.0

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

as.data.frame.boin_boundary	Coerce BOIN Decision Boundaries to a Data Frame
be_boin_simulate	Simulate BE-BOIN Trials
bf_boin_simulate	Simulate BF-BOIN Trials
boin_boundary	Integer Decision Boundaries for the BOIN Design
boin_decision_table	Decision Table for the BOIN Design
boin_isotonic	Isotonic Estimates of the DLT Probability
boin_lambda	Escalation and De-escalation Interval Boundaries
boin_p_tox	Toxic Threshold Giving a Required De-escalation Boundary
boin_select_mtd	Select the MTD from Completed Trials
boin_simulate	Simulate BOIN Trials
boin_stopping_table	Safety Stopping Boundary as a Two-Row Table
comb_boin_next	Next Dose Combination in a BOIN Drug-Combination Trial
comb_boin_select_mtd	Select the MTD Combination from Completed Drug-Combination Trials
comb_boin_simulate	Simulate BOIN Drug-Combination Trials
decision_table_3p3	Decision Table for the 3+3 Design
oc_3p3	Exact Operating Characteristics of the 3+3 Design
plot.boin_decision_table	Plot a BOIN Decision Table
plot.comb_boin_next	Plot the Next Dose Combination of a BOIN Drug-Combination Trial
plot.decision_table_3p3	Plot a 3+3 Decision Table
plot.tite_boin_decision_table	Plot a TITE-BOIN Decision Table
print.backfill_oc	Print Operating Characteristics of a BOIN Design with Backfilling
print.backfill_oc_multi	Print Operating Characteristics of a Backfill Design Across Scenarios
print.backfill_trials	Print Simulated Trials of a BOIN Design with Backfilling
print.boin_boundary	Print BOIN Decision Boundaries
print.boin_decision_table	Print a BOIN Decision Table
print.boin_oc	Print Operating Characteristics of a BOIN Design
print.boin_oc_multi	Print Operating Characteristics Across Scenarios
print.boin_trials	Print Simulated BOIN Trials
print.comb_boin_next	Print the Next Dose Combination of a BOIN Drug-Combination Trial
print.comb_boin_oc	Print Operating Characteristics of the BOIN Drug-Combination Design
print.comb_boin_oc_multi	Print Operating Characteristics of the BOIN Drug-Combination Design Across Scenarios
print.comb_boin_trials	Print Simulated BOIN Drug-Combination Trials
print.decision_table_3p3	Print a 3+3 Decision Table
print.oc_3p3	Print Operating Characteristics of the 3+3 Design
print.tite_boin_decision_table	Print a TITE-BOIN Decision Table
print.tite_boin_oc	Print Operating Characteristics of a TITE-BOIN Design
print.tite_boin_oc_multi	Print Operating Characteristics of a TITE-BOIN Design Across Scenarios
print.tite_boin_trials	Print Simulated TITE-BOIN Trials
sim_3p3	Simulate the 3+3 Design
sim_be_boin	Operating Characteristics of a BE-BOIN Design
sim_be_boin_multi	Operating Characteristics of a BE-BOIN Design Across Several Scenarios
sim_bf_boin	Operating Characteristics of a BF-BOIN Design
sim_bf_boin_multi	Operating Characteristics of a BF-BOIN Design Across Several Scenarios
sim_boin	Operating Characteristics of a BOIN Design
sim_boin_multi	Operating Characteristics Across Several Scenarios
sim_comb_boin	Operating Characteristics of the BOIN Drug-Combination Design
sim_comb_boin_multi	Operating Characteristics of the BOIN Drug-Combination Design Across Scenarios
sim_tite_boin	Operating Characteristics of a TITE-BOIN Design
sim_tite_boin_multi	Operating Characteristics of a TITE-BOIN Design Across Several Scenarios
tite_boin_decision_table	Decision Table for the TITE-BOIN Design
tite_boin_simulate	Simulate TITE-BOIN Trials